EVALUATION OF THE RELATION BETWEEN PLATELET COUNT AFTER PRIMARY PCI AND LEFT VENTRICULAR ANEURYSM IN PATIENTS WITH ACUTE ANTERIOR ST ELEVATION MYOCARDIAL INFARCTION

Mahboobe Gholipour, Seyedeh Fatemeh Mirrazaghi, Mani Moayerifar, Salman Nikfarjam, Arsalan Salari, Marjan Mahdavi roshan, Fardin Mirbolouk, Asiyeh Ashouri, Pouya Pourafshar

Abstract


Objective: To evaluate the relationship between platelet count after primary percutaneous coronary intervention (p-PCI) and left ventricular aneurysm (LVA) in patients with acute anterior ST-elevation myocardial infarction(STEMI).

Methodology: This descriptive study was performed on a population of patients with acute anterior STEMI, who had undergone p-PCI. Sampling was carried out by a consecutive survey of patients, who were admitted to the Medical Center in summer and fall of 2018. Blood samples were collected intravenously from all the patients at admission to the emergency department before and after p-PCI. Echocardiographic examinations were routinely performed by a specialist assistant as the co-author 8 to 12 hours after p-PCI and at follow-up (10 to 14 months after acute MI). The TIMI flow was observed immediately after p-PCI. In all the patients undergoing p-PCI, the location of left anterior descending (LAD) artery involvement during coronary arteries angiography was divided into three sections based on LAD artery length.

Results: The mean WBC and PMN before p-PCI were statistically higher in the group of patients with LVA compared to individuals without LVA (p<0.001). Based on multivariate analysis platelet count (OR=0.999, age (OR=1.07), PMN before P-PCI (OR=1.001) had a significant additive effect on the probability of LVA formation.

Conclusion: Platelet count can be used for prediction of the risk of future LVA formation in acute STEMI patients.

Key words: ST-segment elevation myocardial infarction; platelet count; mortality; percutaneous coronary intervention; left ventricular aneurysm


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