SPECTRUM OF SEVERITY OF CORONARY ARTERY DISEASE AMONG DIABETICS WITH DIABETIC RETINOPATHY

Abstract

Objective: To determine the spectrum of severity of coronary artery disease(CAD) among diabetics with diabetic retinopathy (DR).

Methodology: This cross- sectional study was carried out in Cardiologydepartment, Lady Reading Hospital Peshawar from 11 Nov, 2017 to 10 March,2018. All patients fulfilling the inclusion and exclusion criteria were enrolled instudy by using non-probability sampling. After written, informed consent,patients were subjected to detailed history taking and physical examination,followed by fundoscopic examination of eye and angiography for CAD. Based onfundoscopy patients were classified in non-Diabetic Retinopathy (DR) , preproliferative DR (pre-PDR)and proliferative DR(PDR). Angiographic severity ofCAD categorized patients into non-CAD, mild, moderate and severe CADdepending on number of vessels involved. Data was analyzed in SPSS 20.

Results: Total of 103 patients were included with mean age of 54+ 8.1 years ofwhich 68% were males. Mean duration of DM was 7.1 + 2.6 years, 26.2%patients had history of CAD with 10.6% STEMI and 15:5% NSTEMI, 30.09%patients had no DR while 50.4% and 15.4% were categorized as pre PDR andPRD respectively. About 26.2% patients had no CAD while 36.9%, 21.3% and11.6% fell in category of mild, moderate and severe CAD respectively.

Conclusions: Diabetic Retinopathy and CAD are strongly related and increase instage of Diabetic Retinopathy increases the severity of CAD.