DIAGNOSTIC ACCURACY OF COMPUTED TOMOGRAPHIC ANGIOGRAPHY FOR THE DETECTION OF STENOTIC LESIONS OF THE DISTAL SEGMENTS OF MAIN CORONARY ARTERIES

Abstract

Objective: It was to find out the diagnostic accuracy of CT angiography for the
detection of stenotic atherosclerotic lesions in the distal segments of 4 main
coronary arteries using invasive angiography as gold standard.

Methodology: This observational study was carried out at Department of
Cardiology, Hayatabad Medical Complex, Peshawar. It included 50 patients from
June to September 2011. CT and invasive angiography was performed for each
patient and data was analyzed in SPSS software version 10.0 to analyze the
findings of distal segments of the 4 main arteries.

Results: The sensitivity for detection of stenotic atherosclerotic lesions in left
main stem, left anterior descending, circumflex and right coronary arteries was
87.5%, 100%, 66.67% and 50% respectively. Specificity for detection of stenotic
atherosclerotic lesions in left main stem, left anterior descending, circumflex and
right coronary artery was 100% for all. Positive predictive value for detection of
stenotic atherosclerotic lesions in left main stem, left anterior descending,
circumflex and right coronary arteries was also 100% for all and negative
predictive value was 97.6%, 100%, 97.91% and 95.83% for the left main stem,
left anterior descending, circumflex and right coronary arteries respectively.

Conclusion: Invasive angiography is more sensitive than CT angiography but has equal specificity to invasive angiography for the detection of stenotic lesions in the distal segments of 4 main coronary arteries.