COMPARISON OF CORONARY ARTERY DIAMETER AMONG PATIENTS WITH AND WITHOUT DIABETES MELLITUS

Abstract

Objective: To compare the coronary arteries diameter between diabetic and nondiabetic
patients undergoing coronary angiography.
Methodology: This cross sectional comparative study was carried out in cardiac
catheterization laboratory, from January to June 2010. Patients were divided into
two groups; diabetics and nondiabetics. Coronary angiography was performed
and quantitative analysis of coronary segments was performed.
Results: A total of 278 patients, 139 in each group were included in the study.
Mean age±SD (years) in diabetic and nondiabetic groups was 52.8±7.531 V
52.9±6.79; P=0.91 respectively. Hypertension among diabetics and non
diabetics were66(47%)V 59(42.4%) P=0.39 respectively. Left main stem
coronary artery (LMS) in diabetics and non diabetics were 4 V 4.18 P=0.008
respectively. Proximal segments of left anterior descending (LAD) coronary
artery sizes in diabetics and non-diabetics were 2.99 V 3.1P =0.000 while mid
and distal segments were 2.95 V 3.14 P=0.000 and 1.95 V 2.42 P=0.000
respectively. Sizes of various segments of proximal left Circumflex (LCx)
coronary artery in diabetics and non-diabetics were 2.99 V 3.0 P=0.37 while
distal circ 1.85 V 2.29 P=0.000 respectively. Proximal segments of right
coronary artery in diabetic and nondiabetic group were 3.02±0.25mmV
3.18±0.25mm; P=0.000 while mid and distal segments were 2.99±0.26V
3.18±0.25; P=0.000 and 2.43±0.51V2.87±0.32; P=0.000 respectively.
Conclusion: In this study, coronary arteries in diabetic patients were found to be
narrower than in Non diabetic subjects. The right coronary artery , left main stem,
left anterior descending and distal circumflex arteries were more significantly
affected in diabetics and proximal circumflex was not significantly affected.