ASSOCIATION BETWEEN HELICOBACTER PYLORI INFECTION AND ACUTE MYOCARDIAL INFARCTION (AMI)

Abstract

Objective: To determine the association between helicobacter pylori infectionand acute myocardial infarction.

Methodology: A six months case-control study was conducted at CardiologyDepartment of Liaquat Medical University Hospital, Jamshoro. The studycomprised of patients presenting with acute myocardial infarction (cases)admitted with myocardial injury and controls that were volunteer individuals. Therelevant laboratory investigations were advised and the data was analyzed usingSPSS version 22.0.

Results: Total 218 individual were evaluated. Of them 109 (50%) were controlsand 109 (50%) were cases during study period. About 110 (50.45%) participantswere males. The mean age of controls was 51.88±.7.90 years and cases50.93±8.13 years with range of 35-65 (t= -.870, p=.385). H-Pylori status waspositive in 75.2% of cases as compared to 41.2% of controls ( 2=5.945,p=.001). Also higher in males 85.4% than females (t=7.348 and p=.000).

Conclusion: It was concluded that H-Pylori infection was significantly associatedwith patients compared to controls. Therefore,monitoring of H-Pylori infection as a possible risk factor of coronary arterydisease may be of clinical value.