ROLE OF QRS DURATION AND MORPHOLOGY IN PREDICTING RESPONSE TO CARDIAC RESYNCHRONIZATION TREATMENT

Abstract

Cardiac resynchronization therapy (CRT) has become
a standard treatment for patients with congestive
heart failure (CHF) who remain symptomatic despite
maximum medical therapy.Prognostic Role of QRS in Medical Population.
QRS duration predicted mortality in approximately
47000 patients that comprised a general medical
population.Magnitude of QRS Shortening and CRT
Response.More recently use of multi-parameter approach in
both wide62 and narrow63 QRS patients has been used
with a significant improvement in sensitivity and
specificity.More prospective, randomized studies need
to be conducted to evaluate role of CRT in narrow
QRS patients using multi asynchrony parameter
approach. In the meantime responder rate amongst
those currently eligible for CRT needs to be improved
by focusing on role of viability, coronary sinus
venous anatomy, site of electromechanical delay, and
pacemaker optimization.