FREQUENCY OF HIGH TIMI SCORE AND ITS SHORT TERM CLINICAL OUTCOMES

Abstract

Objective: To determine the frequency of high thrombolysis in myocardialInfarction(TIMI) risk score and its short term clinical outcomes among patientspresenting with acute ST elevation myocardial infraction.

Methodology: This cross sectional study was conducted at CardiologyDepartment, Lady Reading Hospital, Peshawar from 1st January till 31stDecember, 2012. This study included cases of ST elevation myocardial infarction(STEMI). Thrombolysis in Myocardial Infarction (TIMI) risk score was calculatedfor each case at the time of presentation. Patients were followed during theirhospital stay and immediate post discharge days for the occurrence ofcomplications like cardiogenic shock, arrhythmias, mortality etc.Results: A total of 385 patients with acute myocardial infarction were included.Out of 385 patients, high TIMI score was found in 122 (31.84%). Out of 122cases, males were 79(64.75 %). Mean age was 56.71 ± 10.00 years. Among122 patients, 55(45.5%) had score of 9, 12(9.9%) had score of 10, 43(35.5%)had score of 11and 11(9.1%) had score of 12. Ventricular fibrillation was presentin 21(17.4%), VT in 15(12.4%), atrial fibrillation 1(0.8%) and complete heartblock in 8(6.61%). cardiogenic shock in 29(24.0%), pulmonary edema in33(27.3%) and In-hospital death in 22(18.2%). Post infarct Angina in 39 (32.2%),stroke occurred in 11(9.1%) and 30(24.8%) underwent revascularization.

Conclusion: High TIMI risk score correlates significantly with death andcomplications like cardiogenic shock and arrhythmias in early post-infarctionperiod. Frequency of complication increases with the increasing score.