ANTICOAGULANT TREATMENT AT A SPECIALIZED OUTPATIENT ANTICOAGULATION SERVICE, A DESCRIPTIVE STUDY

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Siddra Ahmed Khan , Saeed Ullah Shah , Muhammad Asad Ali Saleem, Yusuf Hassan , Asaad Akbar Khan, Kashif Jan , Muhammad Abdul Azeem , Hira Mahmood

Abstract

Objectives: ACR (Anticoagulation registry aims to record information about the health
status of their registered patients and the health care they receive over varying periods
for a particular disease requiring anticoagulation. (e.g., Warfarin, Novel Oral
Anticoagulants, and Parenteral Heparins). It’s the male and female prevalence and the
mean age the patients are presenting in. Further, to foresee the development of a
nationwide Anticoagulation network which will provide a nidus for developing specific
disease-based registries.
Methodology: A retrospective observational study of 1695 registered patients in the ACR
since 2018. The registered patient’s data was analyzed using SPSS version 23.0. Variables
so far defined and analyzed were demographic distribution, gender, age, indications for
anticoagulation.
Results: There were 799 (47.1%) female and 896 (52.86%) male patients requiring
anticoagulation with a mean age of (54.37 +/- 17.79 SD) years. The primary indication
for anticoagulation in our registry was Thrombosis and Thromboembolism 787/1695
patients (34.90%), Cardiac prosthesis 540/1695 patients (24.06%), Atrial Fibrillation
and Atrial Flutter 486 patients (21.50%). 266/1695 (11.81%) are in the registry as they
have Rheumatic Heart disease requiring anticoagulation .55/1695 (2.44%) of patients
are registered with us due to Intra-cardiac devices implantation requiring
anticoagulation—the remaining anticoagulation needed due to other reasons, which
were cardiac and non-cardiac as well. The proportion of females with atrial fibrillation
was significantly higher than male patients, 33.6% vs. 24.5% (p=0.000). Moreover, in
Age distribution, most patients are between 61 years to 70 years of age. Geographically
most of the patients are from the Punjab Province.
Conclusion: ACR annual report will allow healthcare professionals to see which
disease requiring anticoagulation is prevalent in our setup. It illustrates different
approaches to anticoagulation therapy. Registry further informs how the patients
responded to anticoagulation, the safety with which the anticoagulation was terminated
after treatment of the disease in short-duration anticoagulation cases, and the outcome
of patients in lifelong anticoagulation cases. Currently, we are working on how to store
the data on the disease-specified target range. This will help us establish the importance
of ACR in anticoagulation management.

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